The Leeds Teaching Hospitals NHS Trust

Intra-Uterine Insemination (IUI)

What is IUI and how is it done?

This is a technique where a preparation of most healthy and progressively motile sperm from your partner is injected through the neck of the womb (cervix) into the cavity of the uterus using a fine tube. Very occasionally following this procedure you may get cramp-like pains in the uterus, which are similar to period pains.

The sperm preparation takes approximately one and a half hours after the sample has been handed to the embryologist to prepare. It involves washing and concentrating the normally formed and progressively motile sperm and separating them from those that are not well formed and those that have poorer survival and motility. We request your partner to give us a fresh sample for this purpose although in difficult situations we can use previously provided and frozen sperm.

When is it performed?

  1. Usually when we perform induction of ovulation with gonadotrophins, we combine that with an IUI because there is medical evidence that success rate improves in doing so.
  2. IUI is not routinely performed when ovulation is induced with clomifene and / or metformin unless specifically requested by the patient. This is because the evidence for its benefit in couples where timed sexual intercourse is possible is not as strong in this group.
  3. However we may choose to do an IUI when there is a specific indication such as difficulty in having timed sexual intercourse.

Instructions after the IUI

At the time of ovulation you may experience lower abdominal discomfort which should settle within that day.

If any pain persists or you are worried at all please contact the unit and speak to a doctor or nurse.

You may continue your normal activities as usual.

If you require any further medication it will be prescribed on a treatment sheet. Please check with the unit or your GP before taking any other medications.

It is very important that you inform the unit nurses about the outcome of any treatment cycle.

It would be helpful if you could either ring or e-mail Ayesha Boadle-Soumah
Telephone: 0113 2063172

Clearly state your name, date of birth, date of your insemination and whether or not you are pregnant

E-mail:  Ayesha.boadle-soumah(at) This email address is being protected from spambots. You need JavaScript enabled to view it.

Put 'IUI result' in the heading and in the text state your name, date of birth, date of your insemination and whether or not you are pregnant.

If I do not hear from you I may need to ring you to follow up the result.

If you are not pregnant your period should arrive approximately 14 days after the insemination. The date of when your pregnancy test becomes due will be given to you at the time of the insemination. On the date given, you can either perform your own pregnancy test at home or you can contact us to arrange to have the test performed on the unit.

Following pregnancy test / or the start of your next period you need to ring the unit and let us know:

If you wish to continue with another treatment cycle in which case we will arrange your next appointment. The telephone number to arrange appointments is 0113 2063111.

If you do not want to start treatment straight away or want to end treatment. In this instance, please ask to speak to one of the nurses. If you wish to speak to a nurse or doctor the receptionist will transfer your call to the appropriate office.