Amiodarone
Amiodarone is an iodine-containing anti-arrhythmic drug which can affect thyroid function tests. Clinical indication for request: Investigation of toxicity.
| Tube | 04 (EP) - EDTA Plasma |
|---|---|
| ID | Tests&Tubes0149 |
| Additional Information | Amiodarone has a similar structure to that of thyroid hormones and interferes in the peripheral conversion of T4 to T3. Resulting T4 levels may be high with a low T3 and an increase in rT3. TSH levels may be raised. Furthermore the iodine content of amiodarone can itself cause a hyperthyroid state although this is less common. Basal TFTs should ideally be checked prior to initiation of amiodarone therapy. Assessment of thyroid function once amiodarone therapy has started should be based upon careful clinical examination |
| Turn Around | Turnaround time stated by Cardiff: 7 days |
| Send to | Blood Sciences LGI (Test referred to: Cardiff toxicology lab) |
| Contact | For further details please contact Leeds Pathology customer services: leedsth-tr.pathologycustomerservice@nhs.net. |
| Advice | Full information on all referred tests can be found on the referred tests information database, EQMS reference BSF2REC17003. |
| Collection Con | Instructions to lab: Centrifuge sample, separate and freeze plasma. Minimum 1mL plasma. |
| Sample REQ | Blood |
| Ref. Range Notes | 0.5 - 2 mg/L |
| Units | mg/L |
| Telepath | LGI superset LAMIO; SJUH superset JAMIO |
