The Leeds Teaching Hospitals NHS Trust

CSF Neurotransmitters (Monoamine metabolites)

CSF HVA and 5-HIAA measurements provide both diagnostic information and treatment monitoring for patients with inborn errors of neurotransmitter metabolism, movement disorders in both children and adults and other neurological disorders affecting the dopamine and serotonin pathways.

ID Tests&Tubes0220
Additional Information Special collection tubes (Set of 3) and dry ice are required. Collect tubes, dry ice, forms and instructions from Biochemistry on day of procedure.
Turn Around Turnaround time stated by the Neurometabolic Unit: 30 working days.
Send to Blood Sciences LGI
(Test referred to: the Neurometabolic Unit, Queen Square, London)
Contact For further details please contact Leeds Pathology customer services:
Advice Full Referred Test details logged internally on the referred test database [BSF2REC17003]
Collection Con Minimum Volume: Tube 1: 0.5 mL for HVA & 5HIAA. Tube 2: 0.5 mL.
Tube 3: contains preservative DTE DETAPAC, 1.0 mL for Pterin analysis.

CSF must be collected into special tubes provided by the Biochemistry lab, and snap frozen on dry ice. Please contact the lab (x26922) the day before the lumbar puncture to arrange. Due to the expense of this test, samples are only dispatched to the Neurometabolic Unit (London) on request. Otherwise, samples are stored for 6 months. **Forms must be returned with the samples**. Instructions to lab: Store in safe-haven box at -80 C until dispatch.
Sample REQ CSF
Ref. Range Notes Reference ranges and interpretation will be provided on the report.
Telepath NEUT1R & SA1R