Lithium
Drug used in treatment of depression. Therapeutic concentrations are based on samples taken >12h post dose. Routine monitoring of patients is essential. Patients should also have TFT's monitored.
| Tube | 01 (SE) - Serum Gel |
|---|---|
| ID | Tests&Tubes0076 |
| Additional Information | EFFECT OF LITHIUM: <0.4 mmol/L the therapeutic response is poor. Levels between 0.4 - 0.6 mmol/L may possible be beneficial for prophylaxis but the chance of relapse is high. The optimum range is between 0.6 - 0.8 mmol/L. Levels >1.2 mmol/L are associated with the risk of renal impairment. Levels between 1.5 - 3.0 are associated with renal impairment, ataxia, weakness and drowsiness. Above 3.0 mmol/L symptoms include dehydration, confusion, spasticity, seizures and coma. |
| Turn Around | A&E: 1 hour Day Case: N/A In-Patient: 6 Hours Out-Patient: 24 Hours GP: 24 Hours |
| Send to | Blood Sciences Cross Site |
| Contact | For further details please contact Leeds Pathology customer services: leedsth-tr.pathologycustomerservice@nhs.net. |
| Collection Con | Must be > 12 hr post-dose. Minimum volume: 500µl serum Instructions for Lab Staff: Standard lab processing- No special requirements |
| Sample REQ | Blood |
| Ref. Range Notes | Blood Sciences reference ranges are available through the useful information and links page: https://www.leedsth.nhs.uk/a-z-of-services/pathology/blood-sciences/useful-information-and-links/ |
| Units | mmol/L |
| Telepath | LI1L |
| ICE Codes | LLI |
