In many tissues plasmalogens are minor constituents, but in heart tissue nearly 50% of phosphatidylcholine may be in this form. Nervous tissues, testes and kidneys also contain significant amounts of plasmalogens. Clinical indication for requesting: for the investigation and diagnosis of peroxisomal biogenesis defects (Zellweger's spectrum disorders) and Rhizomelic chondrodysplasia punctata (decreased plasmalogens).
|Tube||03 (EB) - EDTA Blood|
|Turn Around||Turnaround time stated by Sheffield Children's Hospital: 3-6 weeks|
|Send to||Blood Sciences LGI
(Test referred to: Sheffield Children's Hospital)
|Contact||For further details please contact Leeds Pathology customer services: firstname.lastname@example.org.|
|Advice||Full information on all referred tests can be found on the referred tests information database, EQMS reference BSF2REC17003.|
|Collection Con||Please inform the Duty Biochemist when sending a sample to the lab (0113 39 26922 option 2). Instructions to lab: Centrifuge sample and wash red cells x3 with saline. Send packed red cells.
Minimum volume: 2 mL whole blood
|Ref. Range Notes||Plasmalogens in red blood cells:
C16 / Palmitate: 0.06 - 0.14
C18 / Stearate: 0.150- 0.28
|Telepath||PGEN1R & SA1R|