The Leeds Teaching Hospitals NHS Trust

Plasmalogens

Plasmalogens

In many tissues plasmalogens are minor constituents, but in heart tissue nearly 50% of phosphatidylcholine may be in this form. Nervous tissues, testes and kidneys also contain significant amounts of plasmalogens. Clinical indication for requesting: for the investigation and diagnosis of peroxisomal biogenesis defects (Zellweger's spectrum disorders) and Rhizomelic chondrodysplasia punctata (decreased plasmalogens).

Tube 03 (EB) - EDTA Blood
ID Tests&Tubes0230
Turn Around Turnaround time stated by Sheffield Children's Hospital: 4 weeks
Send to Blood Sciences LGI
(Test referred to: Sheffield Children's Hospital)
Contact For further details please contact Leeds Pathology customer services: leedsth-tr.pathologycustomerservice@nhs.net.
Collection Con Please inform the Duty Biochemist when sending a sample to the lab (0113 39 26922 option 2). Instructions to lab: Centrifuge sample and wash red cells x3 with saline. Send packed red cells.
Sample REQ Blood
Ref. Range Notes Plasmalogens in red blood cells:
C16 / Palmitate: 0.06 - 0.14
C18 / Stearate: 0.150- 0.28
Telepath PGEN1R & SA1R