The Leeds Teaching Hospitals NHS Trust

Porphyrins (faeces)

Analysis of porphyrin compounds in faeces. Second line investigation of all types of acute porphyria and all types of cutaneous porphyria. If an acute porphyria is suspected, it is essential to request a urine PBG. Urgent PBG analysis is available: urgency will depend upon the clinical condition of the patient and should be discussed with the National Acute Porphyria Service 029 2074 7747. Faecal porphyrin analysis is not available as an urgent test. Interpretation: Increased levels of faecal porphyrins may be seen in PCT, HCP, VP and protoporphyria. Ratio of Coproporphyrin isomers essential for diagnosis of HCP.

ID Tests&Tubes0234
Additional Information Please also send 2x 5mL EDTA blood samples (purple top) for blood porphyrin analysis and 10-20 mL early morning urine for urine porphyrin analysis (unless these have already been sent). PROTECT SAMPLES FROM LIGHT.
Turn Around Turnaround time stated by Cardiff porphyria service: 15 working days
Send to Blood Sciences LGI
(Test referred to: Cardiff porphyria service.)
Contact For further details please contact Leeds Pathology customer services: leedsth-tr.pathologycustomerservice@nhs.net.
Collection Con Please also send an early morning urine sample and 2x EDTA blood tubes. PROTECT ALL SAMPLES FROM LIGHT. Instructions to lab: Sample stable in fridge for 1 day. For longer storage before dispatch, sample must be stored frozen. Note on telepath (specimen comment) whether sample was light-protected. Samples that have not been protected from light are ok to send to Cardiff if < 6h. Samples exposed to light for > 6h should not be sent.
Ref. Range Notes Interpretation will be provided with the report.
Telepath LGI superset LPORFR. SJUH superset JPORFR.