Trimethylamine
Trimethylamine is an organic compound with a strong "fishy" odor in low concentrations. For the diagnosis of primary and secondary trimethylaminuria (Fish Odour Syndrome)
| Tube | 08 (UR) - Urine 24 Hr Chemical Preservative. (Hydrocholric acid preservative required) |
|---|---|
| ID | Tests&Tubes0249 |
| Additional Information | TMAU is associated with ingestion of certain foods and so it is important to collect this sample at the time of the odour. A dietary ‘choline load’ is recommended before collecting the samples by using foods known to produce the odour e.g. beans, eggs, liver. Please contact the duty biochemist if for more information if required. |
| Turn Around | Turnaround time stated by Sheffield Children's Hospital: 6-8 weeks. |
| Send to | Blood Sciences LGI (Test referred to: Sheffield Children's Hospital) |
| Contact | For further details please contact Leeds Pathology customer services: leedsth-tr.pathologycustomerservice@nhs.net. |
| Advice | Full information on all referred tests can be found on the referred tests information database, EQMS reference BSF2REC17003. |
| Collection Con | Ideally, 24h collection collected into 10 mL 6M HCl. Can send 20 mL plain urine in a Universal which can be acidified in the Blood Sciences lab. Instructions to lab: contact Duty Biochemist if sample requires acidification to pH < 2. Send 20 mL. Store sample frozen at -80C Minimum volume: 10 mL urine |
| Sample REQ | Urine |
| Ref. Range Notes | Free TMA/ creat ratio: < 7.7 µmol/mmol crt TMA-N-Oxide / creat ratio: < 119 µmol/mmol crt % N-Oxidation: > 94% Aditional interpretation will be provided on the report. |
| Telepath | TMAU2R |
