Anti-Ganglioside Antibodies

Antibodies to gangliosides are associated with a number of demyelinating neurological diseases including Guillain-Barre syndrome, Chronic demyelinating polyneuropathy and Multifocal motor neuropathy. Also referred to as anti-glycolipid antibodies. Indicated in GBS, multifocal motor neuropathies, motor neurone disease, CIDP, Miller-Fisher syndrome
Tube | Serum Gel |
---|---|
ID | 12790 |
Additional Information | The antibody screen performed by Glasgow includes the detection of IgG and IgM to anti-GM1, GM2, GD1a, GD1b and GQ1b antibodies. If any of these are positive a more extensive panel of tests is performed with end-point dilution analysis. Associated with IgM paraproteins therefore serum electrophoresis should be performed as well. |
Turn Around | Refer to relevant laboratory for up to date turn around times, allowing an additional 10 working days for samples processing, dispatch and reporting and validation of the results. |
Send to | Samples should be sent to the department of Clinical Immunology at LGI who will refer to appropriate referral lab. (Glasgow) |
Collection Con | No restrictions |
Frequency | Referred to external laboratory |
Sample REQ | Blood |
Ref. Range (Male) | See reference range note |
Ref. Range (Female) | See reference range note |
Ref. Range (Paed) | See reference range note |
Ref. Range Notes | Titre >1/500 is positive (Results reported as pos/neg) |
Units | - Not Defined - |
IP Acute TAT | Contact referral laboratory. Contact Immunology at LGI if sample is to be sent urgently. |
IP Routine TAT | Refer to relevant laboratory for up to date turn around times, allowing an additional 10 working days for samples processing, dispatch and reporting and validation of the results. |
GP Acute TAT | Contact referral laboratory. Contact Immunology at LGI if sample is to be sent urgently. |
GP Routine TAT | Refer to relevant laboratory for up to date turn around times, allowing an additional 10 working days for samples processing, dispatch and reporting and validation of the results. |
Telepath | IGM11L |
ICE Codes | IGM1 |