The Leeds Teaching Hospitals NHS Trust

Histone Antibodies

Histone Antibodies

Marker of drug induced lupus. Also found in up to 30% cases of classical SLE. This assay is only performed on samples with a positive homogenous pattern ANA

Tube Serum Gel
ID 12791
Additional Information Highly sensitive and specific marker of Primary Biliary Cirrhosis. Also found in a small percentage of patients with autoimmune chronic active hepatitis. Positive in RA/SLE etc.
Send to Samples should be sent to the department of Clinical Immunology at LGI who will refer to appropriate referral lab (Protein reference unit (PRU) Sheffield.)
Contact https://immqas.org.uk/TestItem.asp?id=457
Advice https://immqas.org.uk/TestItem.asp?id=457
Collection Con No restrictions
Frequency Daily
Sample REQ Blood
Ref. Range Notes See reference range on referral website
Units iu/mL
IP Acute TAT Contact referral laboratory. Contact Immunology at LGI if sample is to be sent urgently.
IP Routine TAT Refer to relevant laboratory for up to date turn around times, allowing an additional 10 working days for samples processing, dispatch and reporting and validation of the results.
GP Acute TAT Contact referral laboratory. Contact Immunology at LGI if sample is to be sent urgently.
GP Routine TAT Refer to relevant laboratory for up to date turn around times, allowing an additional 10 working days for samples processing, dispatch and reporting and validation of the results.
Telepath SIMM1L