Pemphigoid/Pemphigus antibodies
PEMPHIGUS : Autoantibodies directed against desmogleins on the cell surface of epidermal keratinocytes. BULLOUS PEMPHIGOID : Autoantibodies directed against hemidesmosomes in the basement membrane. Both are always tested.
| Tube | Serum Gel |
|---|---|
| ID | 12776 |
| Availability | Weekdays |
| Additional Information | Immunofluorescence of a skin biopsy should also be performed (by Histopathology) as both assays can give false negative results. 70-90% of patients with Pemphigus Vulgaris/ Bullous Pemphigoid have antibodies. Antibody levels may correlate with disease activity for Pemphigus only |
| Turn Around | 10 days |
| Send to | Leeds General Infirmary Clinical Immunology Old Medical School Great George Street Leeds LS1 3EX |
| Collection Con | No restrictions |
| Frequency | Weekly |
| Sample REQ | Blood |
| Ref. Range (Male) | NA Interpretive |
| Ref. Range (Female) | NA Interpretive |
| Ref. Range (Paed) | NA Interpretive |
| Ref. Range Notes | Positive/Negative Positive results are titred |
| Units | - Not Defined - |
| IP Acute TAT | - Contact Laboratory |
| IP Routine TAT | 10 days |
| GP Acute TAT | - Contact Laboratory |
| GP Routine TAT | 10 days |
| Telepath | BULL1L |
| ICE Codes | IBULL |
