The Leeds Teaching Hospitals NHS Trust

Whipples disease

Whipples disease

PCR assay for the detection of Trophymera whipplei - causative agent of “Whipples Disease”
Classic Whipple’s Disease is associated with intermittent arthralgia or chronic digestive disorder with diarrhoea and/or weight loss.
Other common manifestations include endocarditis and neurological symptoms as well as chronic localised infections such as adenopathy, uveitis, pulmonary and joint infections. T.whipplei has also been associated with acute infections such as pneumonia , gastroenteritis and bacteraemia


Tube White top universal
ID 3680
Availability Twice weekly
Turn Around 5 days
Send to LGI Microbiology Department
Collection Con Blood and CSF samples are the most commonly received sample types for this test although a number of samples may be suitable, eg. Heart valves, ,synovial fluid, paraffin embedded tissue and fresh tissue. Send in sterile universal. If unsure contact laboratory.
IP Routine TAT 5 days
GP Routine TAT 5 days