The Leeds Teaching Hospitals NHS Trust

Chromogenic FVIII assay

Chromogenic FVIII assay

Determination of FVIII using a chromogenic method

Tube 05 (CP) - Citrate
ID 12736
Availability Weekdays
Additional Information FVIII activity assays (FVIII:C) are performed to diagnose hemophilia A and to monitor FVIII replacement therapy. FVIII:C assays are typically 1-stage clotting assays. However, there is a subset of mild hemophilia A patients who have shown discrepantly low results when measured with the 2-stage (chromogenic) assay, indicating that testing patients with a mild bleeding history with both a 1- and 2-stage assay would aid in diagnosis.
Send to Specialist Coagulation
Chancellor / Lincoln Wing Link Corridor
Pathology
Block 32
St James University Hospital
Beckett Street
Leeds
LS9 7TF
Contact https://www.leedsth.nhs.uk/a-z-of-services/pathology-2/specialist-laboratory-medicine-slm/specialist-coagulation/?stage=Stage
Collection Con All citrate tubes filled to line please - 2 citrate samples required.
Samples must be processed within 6 hours of being taken.
Sample REQ Blood
Ref. Range (Male) 50-100
Ref. Range (Female) 50-100
Ref. Range (Paed) 50-100
Ref. Range Notes Currently not a diagnostic test
Units iu/dL
IP Acute TAT Contact laboratory
IP Routine TAT 14 days
GP Acute TAT Contact laboratory
GP Routine TAT 14 days
Telepath F8CH1J
ICE Codes LF8CH