Platelet Nucleotides

The nucleotides ATP and ADP are stored in the dense granules of platelets and are utilised for the initiation/propogation of aggregation. Since they do not participate in any energy-producing reactions of the cell, they are known as the non-metabolic poolThe nucleotides ATP and ADP are stored in the dense granules of platelets and are utilised for the initiation/propogation of aggregation. Since they do not participate in any energy-producing reactions of the cell, they are known as the non-metabolic pool. Storage Pool Disease (SPD) is a platelet function defect due to a lack of dense granules. Certain
Tube | 05 (CP) - Citrate |
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ID | 12744 |
Availability | By pre-arranged appointment only. Assays run Wednesdays and Thursdays. Samples must be delivered to the laboratory by 11:00 am on the day of venepuncture. |
Additional Information | **SAMPLES MUST NOT BE SENT IN THE AIRTUBE** Usually requested as part of a full platelet function study. This test is only available by specialist request from a Haematology Consultant and should be discussed with a member of the Haemostasis consultant team before arriving into the laboratory. All platelet testing is prearranged with the laboratory before samples are taken to ensure that relevant trained staff are available on the day to process the tests and ensure that we have contact information for the requestor. |
Turn Around | 4 weeks |
Send to | Specialist Coagulation Chancellor / Lincoln Wing Link Corridor Pathology Block 32 St James University Hospital Beckett Street Leeds LS9 7TF |
Contact | https://www.leedsth.nhs.uk/a-z-of-services/pathology/specialist-laboratory-medicine-slm/specialist-coagulation/ |
Collection Con | **SAMPLES MUST NOT BE SENT IN THE AIRTUBE** Citrate x 8 minimum if requested as part of a platelet function analysis. Citrate x 4 if requested in isolation as a follow up test. All samples must be correctly filled. |
Sample REQ | Blood |
Ref. Range Notes | Total ATP: 25.5 - 68.9 nM/109 plts. Total ADP: 12.8 - 39.7 nM/109 plts Released ATP: 4.1 - 18.9 nM/109 plts Released ADP: 5.3 - 28.5 nM/109 plts Total ATP:ADP Ratio: 1.24 |
Units | nmol/10^9 platelets |
Telepath | PN1J |
ICE Codes | PN1J |