Plasma copper is measured to screen for Wilson's disease and for nutritional assessment.
|Availability||Weekdays. Contact laboratory if urgent analysis is required.|
|Additional Information||Risk factors for nutritional copper deficiency include intestinal failure, malabsorption particularly in the upper GI tract including after bariatric surgery, and excessive zinc supplementation/ingestion. Diagnosis of Wilson's disease can be complex. A plasma copper within or above the reference range cannot exclude Wilson's. A full assessment should be made including 24 hour urine copper, serum caeruloplasmin, examination for Kayser-Fleischer rings and (where indicated) tissue copper estimation in a liver biopsy specimen. Individuals who are heterozygous for Wilson's disease or acaeruloplasminaemia are generally asymptomatic and may have a plasma copper concentration below the lower limit of the reference interval.|
|Turn Around||7 days|
|Send to||Specialist Laboratory Medicine,
St James's University Hospital,
|Collection Con||For paediatric samples 0.5mL heparinised blood would be suitable.|
|Sample REQ||Centrifuge and separate by hand to avoid sample contamination. Store at 4C prior to sending.|