Renin Activity (PRA)
Renin is secreted from the kidney and converts angiotensinogen to angiotensin. The latter stimulates aldosterone production.
|Additional Information||Unexplained Hypertension.|
|Turn Around||21 days|
|Send to||Specialist Laboratory Medicine
St James hospital
|Collection Con||Renin is activated when on ice which invalidates the test. Send to the laboratory ASAP but NOT on ice. Please use a red bag to ensure prompt attention. NOTE the tube required for this test is heparin without gel. (Green and black top) EDTA tube also acceptable. Instructions for lab staff: Sample must be separated and frozen within 4 hours of receipt.|
|Ref. Range (Male)||0.5-3.5|
|Ref. Range (Female)||0.5-3.5|
|Ref. Range (Paed)||Values can be very high (>50) in the neonate|
|Ref. Range Notes||Affected by age (decreased in the elderly), posture, state of hydration & electrolyte status.
|IP Routine TAT||21 days, note if requesting both PRA and aldosterone, and only one sample is received, our quoted TAT is 30 days.|