Vitamin A is one of the fat soluble vitamins. It is essential for normal vision and structure and function of the skin and mucous membranes. It has an essential role during embryogenensis and development. If taken in excess it is hepatotoxic and can interfere with calcium and bone metabolism. During pregnancy excess vitamin A can be teratogenic. Vitamin E is measured at the same time.
|06 (HP) - Heparin No Gel preferred, 02 (SE) Serum No Gel also acceptable
|Plasma vitamin A concentration may fall during the inflammatory response independent of status. CRP should be requested to aid interpretation. Vitamin A metabolism is altered when renal function is impaired. Plasma concentration in this case may be very high and the risk of toxicity is thought to be increased.
|First Class post to: Specialist Laboratory Medicine, Block 46, St James’s University Hospital, Beckett Street, Leeds, LS9 7TF
|Collect after overnight fast where possible or 8 hr post treatment if on oral supplements or parenteral nutrition.
|Protect samples from light as much as possible. Separate and freeze plasma ideally on day of collection. Minium volume = 150 uL plasma.