The Leeds Teaching Hospitals NHS Trust



This is an international randomised controlled trial, looking at the effect of a number of different drugs has on those with significant community-acquired pneumonia.   It is targeted towards those who are in ICU.  Those who are on a Covid-19 ward should be directed towards the Recovery Trial.


This is a study which is considered a national priority.


Participants will be randomised into one of a number of treatment arms, depending on local drug availability, including

  • steroids,
  • macrolides,
  • antivirals and
  • immunomodulators 

Who can participate?

Patients will be eligible if they are

  1. Adults admitted to ICU
  2. Symptoms
  3. Confirmation of SARS-CoV-2 infection by PCR
  4. No medical history that might, in the opinion of the attending clinician, put the patient at significant risk if he/she were to participate in the trial. The R&I Team have expertise to be able to guide on this.

External Trial Website

For more information please contact the COVID19 LTHT Research Delivery team via text or call on their new mobile phone number 07557326811 or email them on