The Leeds Teaching Hospitals NHS Trust

What we do

Immunology Service

The Immunology Service provides facilities for the investigations, diagnosis and treatment of a wide range of primary immunodeficiency diseases and disorders of immune dysregulation including:

  • Antibody deficiency
  • C1 inhibitor deficiency
  • Combined immune deficiency
  • Neutrophil defects
  • Complement deficiency
  • Hyper IgE syndromes, Wiskott Aldrich syndrome, Ataxia Telangiectasia and other primary immunodeficiencies
  • Innate immune deficiencies
  • Periodic fever syndromes
  • Autoinflammatory disorders
  • IgG4 related disease
  • Allergy Services

The service provides facilities for diagnosis, treatment, support and advice for patients with a variety of allergic disorders, including 

  • Airborne allergen hypersensitivity
  • Food allergy
  • Venom allergy
  • Urticaria and Angioedema
  • Anaphylaxis
  • Adverse drug reactions
  • Anaesthetic reactions
  • Subcutaneous and sub-lingual Allergen immunotherapy (desensitisation)
  • Oral challenge test

The unit undertakes joint clinics with a number of different specialties:


  • Autoinflammatory disorders
  • Connective Tissue diseases
  • Vasculitis


  • Complex urticaria
  • Cutaneous Vasculitis
  • Autoinflammatory disorders


  • Complex asthma


There is a facility for medical assessment for patients with a possible diagnosis of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis - CFS/ME unit based at Seacroft Hospital.