The Leeds Teaching Hospitals NHS Trust

What we do

We look after children who have, or might have, a serious problem with their immune system. Many children seem to get a lot of infections, and for most children this is a normal part of growing up, and does not mean they have a weak immune system.

We like to see those children who are having severe or unusual infections, or where there is a family history of recurrent infections, or where the infections are affecting their growth. We see children who have been shown to have low immunoglobulin levels, and children who have seen a paediatrician who is worried they might have a serious immunodeficiency.

Most children we see will fall into one of three groups:

  1. Children requiring assessment for a possible immune deficiency.
  2. Children with a diagnosed immune deficiency. These patients receive regular review and treatment through our outpatient and inpatient services.
  3. Children who have undergone a bone marrow transplant for an immune deficiency. The care of these patients is shared with the bone marrow transplant and immunology team at the Great North Children’s Hospital in Newcastle, where the bone marrow transplant is performed.

Most of our patients are seen in the Children’s outpatient department at Leeds General Infirmary. We currently run one Paediatric Immunology clinic per month. The clinic team includes a Clinical Nurse Specialist, two Consultant Paediatricians from the Leeds Children’s Hospital, an adult Consultant Immunologist (based at St James’ Hospital in Leeds), and a Professor in Paediatric Immunology (based in Newcastle).

Occasionally, it may be necessary for children to stay in hospital. This may be on the day ward, for certain treatments, or on the children’s inpatient wards.

We provide a home immunoglobulin replacement therapy service for those children and young people who have been shown to have low immunoglobulin levels. Children who have such a severe immunodeficiency that they require a bone marrow transplant go to the Great North Children’s Hospital in Newcastle to have the transplant.

We work within a wider multidisciplinary team of health professionals who are available to help each of our patients if needed. These include, but are not limited to, specialist pharmacists, dieticians, dentists, physiotherapists and the children’s surgical team. This means that here in Leeds we are able to offer the best possible care for children with immune deficiencies.

When young people with a primary immunodeficiency graduate into adulthood, their care moves over to the adult immunology service based at St James’s University Hospital.