ADAMTS13 cleaves Von Willebrands factor into smaller multimers. A deficiency of ADAMTS 13, or inhibition of ADAMTS13 activity leads to very large Von Willebrands multimers being released into the circulation. These activate platelets causing aggregation and the formation of micro-thrombi. The poor prognosis associated with TTP requires early, accurate diagnosis.
Tube
05 (CP) – Citrate
Availability
Weekdays
Additional Information
Also known as Von Willebrands cleaving protease. Test is performed at Royal Hallamshire Hospital, Sheffield.
Send to
Specialist Coagulation
Centre for Laboratory Medicine
St James University Hospital
Beckett Street
Leeds LS9 7TF
Contact
Collection Con
2 x Citrate tube filled to line please
Sample REQ
Blood
Ref. Range (Male)
53.0 to 149.0
Ref. Range (Female)
53.0 to 149.0
Ref. Range (Paed)
53.0 to 149.0
Units
iu/dL
IP Acute TAT
24 hours
IP Routine TAT
5 days
GP Acute TAT
Contact Laboratory
GP Routine TAT
Contact Laboratory