Antibodies to adrenal cortex are present in up to 80% patients with primary Addison’s disease at diagnosis but the frequency of positive antibodies decreases with time. Detected by indirect immunofluorescence with multiblock slides that also have ovary and testis tissues. Positive antibodies are suggestive of an autoimmune cause of Addison’s disease.
Tube
Serum Gel
ID
12747
Availability
Weekdays
Additional Information
Also found in patients with Autoimmune Polyglandular Syndromes (APGS) (Type I (APECED) and Type II that have Addison’s disease)
Turn Around
10 days
Send to
Clinical Immunology
E Floor, Old Medical School, LGI
Great George Street
Leeds
LS1 3EX
Contact
https://www.leedsth.nhs.uk/a-z-of-services/pathology/specialist-laboratory-medicine-slm/immunology-laboratory/
Advice
https://www.leedsth.nhs.uk/a-z-of-services/pathology/specialist-laboratory-medicine-slm/immunology-laboratory/
Collection Con
No restrictions
Frequency
Weekly
Sample REQ
Blood
Ref. Range Notes
Qualitative – negative/positive
IP Routine TAT
10 days
GP Routine TAT
10 days