Not active in Blood Sciences Measurement of alpha-1 antitrypsin is useful in the investigation of emphysema and unexplained liver disease in adults. In paediatric practice, alpha-1 antitrypsin deficiency may be associated with neonatal jaundice.
Tube
01 (SE) – Gel Immunology
ID
Tests&Tubes0007
Additional Information
Samples with an AAT concentration of 0.9g/L or below will undergo phenotypic analysis by isoelectric focusing to determine if the patient has one or more (heterozygosity or homozygosity) AAT deficiency alleles.
Users will be asked to contact the lab if alpha1-antitrypsin levels are borderline to clarify if phenotyping is required. Note, AAT levels may be within normal range in paediatric patients, therefore if there is a strong suspicion of AAT deficiency AAT phenotyping should also be performed.
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Clinical Immunology (LGI)
Contact
For further details please contact Leeds Pathology customer services: [email protected]
Collection Con
Instructions for Lab Staff: Standard lab processing – No special requirements
Sample REQ
Blood