Antibodies to gangliosides are associated with a number of demyelinating neurological diseases including Guillain-Barre syndrome, Chronic demyelinating polyneuropathy and Multifocal motor neuropathy. Also referred to as anti-glycolipid antibodies. Indicated in GBS, multifocal motor neuropathies, motor neurone disease, CIDP, Miller-Fisher syndrome.
Tube
Serum Gel
ID
12790
Additional Information
The antibody screen performed by Glasgow includes the detection of IgG and IgM to anti-GM1, GM2, GD1a, GD1b and GQ1b antibodies. If any of these are positive a more extensive panel of tests is performed with end-point dilution analysis. Associated with IgM paraproteins therefore serum electrophoresis should be performed as well.
Turn Around
Due to extended service pressures please note our TAT have been temporarily extended by 6 weeks beyond the times stated above/below. Please do not contact the lab before this time frame unless there is a clinically urgent need.
Send to
Samples should be sent to the department of Clinical Immunology at LGI who will refer to appropriate referral lab. (Glasgow)
Collection Con
No restrictions
Frequency
Referred to external laboratory
Sample REQ
Blood
Ref. Range (Male)
See reference range note
Ref. Range (Female)
See reference range note
Ref. Range (Paed)
See reference range note
Ref. Range Notes
Titre >1/500 is positive
(Results reported as pos/neg)
Units
Not defined
IP Acute TAT
Contact referral laboratory. Contact Immunology at LGI if sample is to be sent urgently.
IP Routine TAT
Due to extended service pressures please note our TAT have been temporarily extended by 6 weeks beyond the times stated above/below. Please do not contact the lab before this time frame unless there is a clinically urgent need.
GP Acute TAT
Contact referral laboratory. Contact Immunology at LGI if sample is to be sent urgently.
GP Routine TAT
Due to extended service pressures please note our TAT have been temporarily extended by 6 weeks beyond the times stated above/below. Please do not contact the lab before this time frame unless there is a clinically urgent need.