Beta-2 microglobulin (B2M) is a transmembrane protein found on all cells that carry HLA antigens. Free B2M is a product of cell breakdown. After filtration through the glomeruli B2M is reabsorbed and catabolized by the proximal tubular cells.
Tube
Immunology
ID
12753
Availability
Weekdays.
Additional Information
In Multiple Myeloma B2M is a prognostic marker and is used to monitor disease activity. Concentrations are raised in renal tubular dysfunction irrespective of cause. Refer to the International staging system for Multiple Myeloma (serum B2M <3.5mg/L in stage I, >5.5mg/L in stage III).
Turn Around
Due to extended service pressures please note our TAT have been temporarily extended by 6 weeks beyond the times stated above/below. Please do not contact the lab before this time frame unless there is a clinically urgent need.
Send to
Leeds General Infirmary
Clinical Immunology
Old Medical School
Great George Street
Leeds
LS1 3EX
Collection Con
No restrictions
Frequency
Daily.
Sample REQ
Blood.
Ref. Range (Male)
1.09 to 2.53
Ref. Range (Female)
1.09 to 2.53
Ref. Range (Paed)
1.09 to 2.53
Units
mg/L
IP Acute TAT
Contact Laboratory.
IP Routine TAT
Contact Laboratory.
GP Acute TAT
Contact Laboratory.
GP Routine TAT
Contact Laboratory.