5-alpha-reductase converts testosterone, DHEA and androstenedione into DHT. DHT is responsible for external mascularisation of males. Hence its deficiency leads to ambiguous genitalia in males. Circulating concentrations are of little significance in females.
Tube
Serum Gel
ID
12632
Availability
Monthly.
Additional Information
To investigate ambiguous genitalia in neonates and young children. To investigate suspicion of 5alpha- reductase deficiency. Very low levels could indicate an enzyme deficiency.
Turn Around
35 days.
Send to
Specialist Laboratory Medicine
Block 46
St James hospital
Beckett Street
Leeds
LS9 7TF
Contact
For further details please contact Leeds Pathology customer services: [email protected].
Advice
01132064717, [email protected]
Collection Con
No restrictions.
Sample REQ
Blood.
Ref. Range (Male)
0.4 to 1.9.
Ref. Range (Female)
<0.5
Ref. Range (Paed)
Paediatric samples – no ranges, interpretive comment added for HCG tests.
Units
nmol/L
IP Routine TAT
35 days.
GP Acute TAT
35 days.
GP Routine TAT
35 days.