Cardiac anti-arrhythmic drug. Acts by blocking fast sodium channels. For monitoring purposes, blood should not be drawn until a steady state has been attained. Clinical indication: therapeutic drug monitoring of flecainide.
ID
04 (EP) – EDTA Plasma
Additional information
Normal dose in adults is 200-400 mg/day. Excreted unchanged in urine. Half life is 14 hours, 20 hours if have ventricular arrhythmias. Steady state plasma levels achieved after 3-5 days of treatment.
Turn around
Turnaround time stated by Cardiff: 7 days
Send to
Blood Sciences LGI
(Test referred to: Cardiff toxicology lab)
Contact
For further details please contact Leeds Pathology customer services: [email protected].
Advice
Full information on all referred tests can be found on the referred tests information database, EQMS reference BSF2REC17003.
Collection Con
Instructions to lab: Centrifuge, separate and freeze plasma. Minimum 1ml plasma.
Sample REQ
Blood
Ref Range Notes
Therapeutic range 0.15 – 0.90 mg/L
Units
mg/L