Quantitation of the concentration of itraconazole in serum.
Confirmation of adequate levels and alerting to toxic levels in patients receiving itraconazole for treatment or prophylaxis of fungal disease. Patient on itraconazole for at least 7 days.
Container / Tube
Serum sample – Sep Clot Activator tube (LTHT: Red top, yellow inner ring. CHFT / MYTT: Brown top). No additives.
Collection Conditions
Collect sample 5 to 7 days after starting treatment. Min vol 10 ml.
Availability
Assay run Mondays and Thursdays.
Send to
Microbiology Department, Centre for Laboratory Medicine, St James’s University Hospital, Beckett Street, Leeds, LS9 7TF.
Turnaround Time
8 days.
Additional Information
Antifungal agents are assayed by liquid chromatography-tandem mass spectroscopy (LC-MS-MS). The results are highly specific and are not influenced by the use of antifungal combination therapy.
ID
3691