PEMPHIGUS : Autoantibodies directed against desmogleins on the cell surface of epidermal keratinocytes. BULLOUS PEMPHIGOID : Autoantibodies directed against hemidesmosomes in the basement membrane. Both are always tested.
Tube
Serum Gel
ID
12776
Availability
Weekdays.
Additional Information
Immunofluorescence of a skin biopsy should also be performed (by Histopathology) as both assays can give false negative results. 70-90% of patients with Pemphigus Vulgaris/ Bullous Pemphigoid have antibodies. Antibody levels may correlate with disease activity for Pemphigus only.
Turn Around
10 days.
Send to
Leeds General Infirmary
Clinical Immunology
Old Medical School
Great George Street
Leeds
LS1 3EX
Collection Con
No restrictions.
Frequency
Weekly.
Sample REQ
Bloody.
Ref. Range (Male)
NA Interpretive.
Ref. Range (Female)
NA Interpretive.
Ref. Range (Paed)
NA Interpretive.
Ref. Range Notes
Positive/Negative Positive results are titled.
Units
– Not Defined –
IP Acute TAT
Contact Laboratory.
IP Routine TAT
10 days.
GP Acute TAT
Contact Laboratory.
GP Routine TAT
10 days.