In many tissues plasmalogens are minor constituents, but in heart tissue nearly 50% of phosphatidylcholine may be in this form. Nervous tissues, testes and kidneys also contain significant amounts of plasmalogens. Clinical indication for requesting: for the investigation and diagnosis of peroxisomal biogenesis defects (Zellweger’s spectrum disorders) and Rhizomelic chondrodysplasia punctata (decreased plasmalogens).
Tube
03 (EB) – EDTA Blood
ID
Tests&Tubes0230
Turn Around
Turnaround time stated by Sheffield Children’s Hospital: 3 to 6 weeks.
Send to
Blood Sciences LGI
(Test referred to: Sheffield Children’s Hospital)
Collection Con
Please inform the Duty Biochemist when sending a sample to the lab (0113 39 26922 option 2). Instructions to lab: Centrifuge sample and wash red cells x3 with saline. Send packed red cells.
Minimum volume: 2 mL whole blood
Sample REQ
Blood.
Ref. Range Notes
Plasmalogens in red blood cells:
C16 / Palmitate: 0.06 to 0.14
C18 / Stearate: 0.150 to 0.28