The nucleotides ATP and ADP are stored in the dense granules of platelets and are utilised for the initiation/propogation of aggregation. Since they do not participate in any energy-producing reactions of the cell, they are known as the non-metabolic poolThe nucleotides ATP and ADP are stored in the dense granules of platelets and are utilised for the initiation/propogation of aggregation. Since they do not participate in any energy-producing reactions of the cell, they are known as the non-metabolic pool. Storage Pool Disease (SPD) is a platelet function defect due to a lack of dense granules. Certain.
Tube
05 (CP) – Citrate
ID
12744
Availability
By pre-arranged appointment only. Assays run Wednesdays and Thursdays. Samples must be delivered to the laboratory by 11:00 am on the day of venepuncture.
Additional Information
**Samples must not be sent in the Airtube** Usually requested as part of a full platelet function study.
This test is only available by specialist request from a Haematology Consultant and should be discussed with a member of the Haemostasis consultant team before arriving into the laboratory. All platelet testing is prearranged with the laboratory before samples are taken to ensure that relevant trained staff are available on the day to process the tests and ensure that we have contact information for the requestor.
Turn Around
4 weeks.
Send to
Specialist Coagulation
Chancellor / Lincoln Wing Link Corridor
Pathology
Block 32
St James University Hospital
Beckett Street
Leeds
LS9 7TF
Contact
Advice
Collection Con
**Samples must not be sent in the Airtube** Citrate x 8 minimum if requested as part of a platelet function analysis. Citrate x 4 if requested in isolation as a follow-up test. All samples must be correctly filled.
Sample REQ
Blood.
Ref. Range Notes
Total ATP: 25.5 – 68.9 nM/109 plts.
Total ADP: 12.8 – 39.7 nM/109 plts
Released ATP: 4.1 – 18.9 nM/109 plts
Released ADP: 5.3 – 28.5 nM/109 plts
Total ATP:ADP Ratio: 1.24
Units
nmol/10^9 platelets