Plasma proteins are synthesised predominantly in the liver, plasma cells, lymph nodes, the spleen and bone marrow. In the course of disease the total protein concentration and also the percentage represented by individual fractions can significantly deviate from normal values. Changes in the relative percentage of one plasma protein can be due to a change in the percentage of one protein fraction. Often in such cases the amount of total protein does not change. The A/G ratio is commonly used as an index of the distribution of the albumin and globulin fractions. Marked changes in this ratio can be observed in cirrhosis of the liver, glomerularnephritis, nephrotic syndrome, acute hepatitis, lupus erythramotosus, as well as in certain acute and chronic inflammations.
Tube
01 (SE) – Serum Gel
ID
Tests&Tubes0103
Additional information
Must be requested separately, not included part of the LFT profile.
Turn around
A&E: N/A
Day Case: N/A
In-Patient: 6 Hours
Out-Patient: 24 Hours
GP: N/A
Send to
Blood Sciences Cross Site
Contact
For further details please contact Leeds Pathology customer services: [email protected].
Collection Con
Intensive care units, renal unit, transplant unit, patients on IV heparin use lithium-heparin (Green with Yellow ring) tube. Minimum volume: 500µl serum / plasma
Instructions for Lab Staff: Standard lab processing – No special requirements
Sample REQ
Blood
Ref. Range Notes
Units
g/L