Valproate is used in the treatment of absence seizures. It inhibits the enzymes gamma-aminobutyric acid transaminas (GABA) which results in an increased concentration of GABA in the brain. GABA is an inhibitor of pre and post-synaptic discharges in the CNS.
Tube
01 (SE) – Serum Gel
ID
Tests&Tubes0135
Additional Information
For an adult on a single dose of valproate the half life is 16 hrs but for an adult on chronic therapy the half life is only 12 hrs.
Turn Around
A&E: N/A
Day Case: 24 Hours
In-Patient: 24 Hours
Out-Patient: 24 Hours
GP: N/A
Send to
Blood Sciences Cross Site
Contact
For further details please contact Leeds Pathology customer services: [email protected].
Collection Con
Intensive care units, renal unit, transplant unit, patients on IV heparin use lithium-heparin (Green with Yellow ring) tube. Minimum volume: 500µl serum / plasma
Instructions for Lab Staff: Standard lab processing – No special requirements.
Sample REQ
Blood
Ref. Range Notes
Units
mg/L