This assay detects autoantibodies to P/Q-type (a1A) voltage gated calcium channels for the investigation of Lambert-Eaton myasthenic syndrome (LEMS).
Tube
Serum Gel
ID
12796
Additional Information
About half of patients with Lambert-Eaton myasthenic syndrome (LEMS) have small cell lung cancer (SCLC) and 85% have voltage gated calcium channel antibodies. However, VGCC antibodies can also be found at low levels in some patients with lung cancer without LEMS.
Turn Around
Refer to https://www.ouh.nhs.uk/immunology/diagnostic-tests/tests-catalogue/calcium-channel-antibodies for turn around times, allowing an additional 10 working days for sample processing and reporting
Send to
Samples should be sent to the Clinical Immunology laboratory at Old Medical School LGI, who will refer to appropriate referral lab (Oxford).
Contact and advice
Collection Con
No restrictions
Frequency
Referred to external laboratory
Sample REQ
Blood.
Ref. Range (Male)
<45 pM = negative
Ref. Range (Female)
<45 pM = negative
Ref. Range (Paed)
<45 pM = negative
Units
pM