Calcitonin
Calcitonin is produced by parafollicular C-cells of thyroid under calcium control. Calcitonin can also be secreted by small cell carcinoma of the lung, breast carcinoma, renal tubular carcinoma, and carcinoid tumours. Indications for requesting: diagnosis and management of medullary thyroid carcinoma, screening of family members of patients with MTC, screening for MEN II. A single raised levels is sufficient for diagnosis although some patients may require a provocative test. Serial monitoring is useful for assessing recurrence and prognosis. Moderate increases in calcitonin are seen in pregnancy, renal failure and pernicious anaemia.
| Tube | 01 (SE) - Serum Gel |
|---|---|
| ID | Tests&Tubes0162 |
| Additional Information | Samples must be received in the lab within 30 min of collection. **Please note change of methodology & reference range in June 2020.** |
| Turn Around | Turnaround time stated by Sheffield PRU: 14 working days. |
| Send to | Blood Sciences LGI (Test referred to: Sheffield Protein Reference Unit (PRU).) |
| Contact | For further details please contact Leeds Pathology customer services: leedsth-tr.pathologycustomerservice@nhs.net. |
| Advice | Full Referred Test details logged internally on the referred test database [BSF2REC17003]http://leedspath.myeqms.com/Administrator/LoadDocADM.asp?ID=82998&Ext=True&CCID=1 |
| Collection Con | Minimum Volume: 2ml serum. Instructions to lab: Sample must be centrifuged within 30 min of sample collection. Freeze serum. EDTA |
| Sample REQ | Blood |
| Ref. Range Notes | current method 0 - 10.5 ng/L. Previous method < 2 iU/L |
| Units | ng/L |
| Telepath | LGI superset LCATN. SJUH superset JCATN. |
