Calcitonin is produced by parafollicular C-cells of thyroid under calcium control. Calcitonin can also be secreted by small cell carcinoma of the lung, breast carcinoma, renal tubular carcinoma, and carcinoid tumours. Indications for requesting: diagnosis and management of medullary thyroid carcinoma, screening of family members of patients with MTC, screening for MEN II. A single raised levels is sufficient for diagnosis although some patients may require a provocative test. Serial monitoring is useful for assessing recurrence and prognosis. Moderate increases in calcitonin are seen in pregnancy, renal failure and pernicious anaemia.
|Tube||01 (SE) - Serum Gel|
|Additional Information||Samples must be received in the lab within 30 min of collection. **Please note change of methodology & reference range in June 2020.**|
|Turn Around||Turnaround time stated by Sheffield PRU: 14 working days.|
|Send to||Blood Sciences LGI
(Test referred to: Sheffield Protein Reference Unit (PRU).)
|Contact||For further details please contact Leeds Pathology customer services: email@example.com.|
|Advice||Full Referred Test details logged internally on the referred test database [BSF2REC17003]http://leedspath.myeqms.com/Administrator/LoadDocADM.asp?ID=82998&Ext=True&CCID=1|
|Collection Con||Minimum Volume: 2ml serum.
Instructions to lab: Sample must be centrifuged within 30 min of sample collection. Freeze serum. EDTA
|Ref. Range Notes||current method 0 - 10.5 ng/L. Previous method < 2 iU/L|
|Telepath||LGI superset LCATN. SJUH superset JCATN.|