Mitochondrial antibodies
Anti-mitochondrial antibodies are part of an autoantibody screen which includes gastric parietal cell antibodies, liver kidney microsomal antibodies and smooth muscle antibodies that can be detected using mouse liver, kidney and stomach multiblock slides. Part of autoantibodies screen - gastric parietal cell, LKM and smooth muscle antibodies will also be tested.
| Tube | Serum Gel |
|---|---|
| ID | 12770 |
| Availability | Weekdays |
| Additional Information | Multiple anti-mitochondrial patterns are identifiable however the M2 pattern is considered pathognomic of Primary Biliary Cirrhosis (PBC). If an unusual/atypical immunofluorescence pattern is detected immunoblotting is performed for confirmation of anti-M2 type antibody. |
| Turn Around | 7 days |
| Send to | Leeds General Infirmary Clinical Immunology Old Medical School Great George Street Leeds LS1 3EX |
| Collection Con | No restrictions |
| Frequency | Daily |
| Sample REQ | Blood |
| Ref. Range (Male) | NA-Interpretive. AMA semiquantitative |
| Ref. Range (Female) | NA-Interpretive. AMA semiquantitative |
| Ref. Range (Paed) | NA-Interpretive. AMA semiquantitative |
| Ref. Range Notes | Negative/Week/Positive. Positive AMA will be titred. |
| Units | NA |
| IP Acute TAT | - Contact Laboratory |
| IP Routine TAT | 7 days |
| GP Acute TAT | - Contact Laboratory |
| GP Routine TAT | 7 days |
| Telepath | LKS2L |
| ICE Codes | ILKS |
