We passionately believe in offering a world class service through our team of more than 740 dedicated professionals.

Delivering a state of the art diagnostic service

We have a comprehensive list of UKAS accredited tests, and clinical professionals can request our analytical and interpretive services from a range of disciplines.

Microbiology: Sometimes it’s the smallest of things that have all the answers.

Blood Sciences: “750 000 specimens a month, equating to 6 tubes of blood for every person living in Leeds and Bradford”!

SLM: “Providing Specialist Clinical Biochemistry, Clinical Haematology, Clinical and Transplant Immunology services locally for LTHT and regionally for referring labs within WYAAT and beyond.”

Clinical Genetics: Finding answers for families in 3.2 billion letters of genetics code.

Fetal Anomaly Screening (Down's syndrome, Edward's syndrome and Patau's syndome screening)

Combined test performed in the first trimester between 11 weeks 2 days to 14 weeks 1 day of gestation to assess the chance of Down's syndrome (T21) and/or Edwards'/ Patau's syndrome (T18/T13). The laboratory measures free beta human chorionic gonadotrophin (free beta HCG) and pregnancy associated plasma protein-A (PAPP-A).

Quadruple test performed in the second trimester between 14 weeks 2 days to 20 weeks 0 days gestation to assess the chance of T21 only. The laboratory measures alpha fetoprotein (AFP), free beta human chorionic gonadotrophin (free beta HCG), unconjugated oestriol (uE3) and Inhibin-A.

Tube	Serum Gel
ID	29949
Availability	Weekdays
Send to	Specialist Laboratory Medicine Block 46 St James hospital Beckett Street Leeds LS9 7TF
Contact	leedsth-tr.Antenatal@nhs.net
Advice	https://www.gov.uk/topic/population-screening-programmes/fetal-anomaly
Collection Con	Minimum volume: 2 mL Instructions for lab: On receipt of samples, they should be centrifuged (and separated if a non-gel tube is received). Send to Block 46. If storage required (overnight or over the weekend) store refrigerated at 2-8°C. Aliquots (when required) should be appropriately labelled according to the Pathology labelling policy. Screening sample stability acceptance criteria: Whole blood (unseparated) samples can be stored at: •Room temperature (20 degrees Celsius) for 48 hours •4 degrees Celsius for 5 days Serum (separated) samples can be stored at: •Room temperature (20 degrees Celsius) for 72 hours •4 degrees Celsius for 14 days
Frequency	Daily
Sample REQ	Serum
Ref. Range Notes	The results of the biochemistry tests are combined with scan and demographic data in a software program to calculate the risk of the pregnancy being affected by Down’s syndrome, Edward’s syndrome and Patau’s syndrome.