Hydroxyindole Acetic Acid (5-HIAA - urine)
5-hydroxyindoleacetic acid (5HIAA) is a metabolite of serotonin. Measurement of 5HIAA in urine is used to exclude serotonin-secreting neuroendocrine carcinoid tumours as a cause of current symptoms. Features of carcinoid disease or the carcinoid syndrome include flushing, diarrhoea, wheezing and heart disease. Plasma 5HIAA and whole blood serotonin can also be measured and may offer better sensitivity and specificity for the investigation of possible carcinoid disease.
|Tube||24h Acid Urine (Acetic Acid)|
|Additional Information||The following must be avoided for 12 hours before and during the collection period: Banana, tomato, pineapple, avocado, plum, walnuts, pecans, kiwi, chocolate. Any processed food that may contain the above ingredients. Any health food supplements containing 5-Hydroxytryptophan (extract of Griffonia Simplicifolia seed).|
|Turn Around||10 days|
|Send to||First Class Post to: Specialist Laboratory Medicine
|Collection Con||Accurately timed 24 hour collection, dietary advice required before collection. Avoidance of serotonin containing foods necessary. Contact lab before starting urine collection to obtain correct container for this test.|
|Sample REQ||Store at 4C prior to sending.|