The Leeds Teaching Hospitals NHS Trust


Recovery Trial


Summary

In the absence of evidence for the effectiveness of treating Covid-19, this trial is looking at the effectiveness of three new drugs which have been used to treat other conditions.  This is an adaptive study, which means that the results will be closely monitored to see if there are some treatment arms which are more effective than others:  if this is the case, the treatment arm will be stopped. 

Priority

This is a study which is considered a national priority.

Treatment

Participants will be randomised into one of four treatment arms

  • No additional treatment (ie standard care)
  • Lopinavir-Ritonavir: a drug combination used to treat HIV
  • Azithromycin, an antibiotic used to treat bacterial infections
  • Low dose corticosteroids

Who can participate?

Patients will be eligible if they are:

  1. Aged at least 18 years
  2. Hospitalised
  3. Confirmation of SARS-CoV-2 infection by PCR
  4. No medical history that might, in the opinion of the attending clinician, put the patient at significant risk if he/she were to participate in the trial. The R&I Team have expertise to be able to guide on this. 

For more information please contact the COVID19 LTHT Research Delivery team via text or call on their new mobile phone number 07557326811 or email them on leedsth-tr.covid19-researchdeliveryteam@nhs.net.