Gastric Intrinsic Factor Antibodies (GIFab)
The autoimmune destruction of gastric parietal cells (and autoantibody inactivation of intrinsic factor) leads to a lack of intrinsic factor. Since the absorption from the gut of normal dietary amounts of vitamin B12 is dependent on intrinsic factor, the loss of intrinsic factor leads to vitamin B12 deficiency. The loss of ability to absorb vitamin B12 is the most common cause of adult vitamin B12 deficiency.
| Tube | 01 (SE) - Serum Gel |
|---|---|
| ID | Tests&Tubes0070 |
| Additional Information | A GIFab sample should not be collected from a patient who has received a vitamin B12 injection in the last week as free vitamin B12 can give a false positive result. |
| Turn Around | A&E: N/A Day Case: N/A In-Patient: N/A Out-Patient: 168 Hours GP: 168 Hours |
| Send to | Blood Sciences LGI |
| Contact | For further details please contact Leeds Pathology customer services: leedsth-tr.pathologycustomerservice@nhs.net. |
| Collection Con | Samples must be less than 48 hours old when received in the laboratory. Samples from external referral sites must be separated and frozen prior to transport. |
| Sample REQ | Blood Minimum volume 555uL serum |
| Ref. Range Notes | Blood Sciences Refernce ranges available through the useful information and links page: https://www.leedsth.nhs.uk/a-z-of-services/pathology/blood-sciences/useful-information-and-links/ |
| Units | AU/mL |
| Telepath | IFAS2L |
| ICE Codes | LIFAS |
