The Leeds Teaching Hospitals NHS Trust

Parathyroid Hormone (PTH)

Parathyroid Hormone (PTH)

PTH is the major hormone involved in calcium homeostasis, and should always be interpreted alongside a concomitant serum calcium result.

Tube 04 (EP) - EDTA Plasma
ID Tests&Tubes0089
Additional Information PTH has a marked diurnal rhythm with a nadir at 10-11am. If hyperparathyroidism is suspected, we suggest that samples are taken in the mid-morning. Raised levels of PTH in the setting of hypercalcaemia are indicative of primary or tertiary hyperparathyroidism. Symptoms of hyperparathyroidism include “bones” (increased turnover), “groans” (abdominal) and “stones” (renal). Note familial hypocalciuric hypercalcaemia (FHH) can cause diagnostic problems, as PTH may also be raised in this disorder. The two conditions can be differentiated by measuring calcium in a 24 hour urine sample. A normal or unmeasurable PTH in a patient with hypocalcaemia is suggestive of hypoparathyroidism.
Turn Around A&E: N/A
Day Case: N/A
In-Patient: 24 Hours
Out-Patient: 24 Hours
GP: 72 Hours
Send to Blood Sciences Cross Site
Contact For further details please contact Leeds Pathology customer services: leedsth-tr.pathologycustomerservice@nhs.net.
Collection Con ***** IMPORTANT Serum tube also required for Calcium.*****
Instructions for Lab Staff: Standard lab processing- No special requirements
Sample REQ Blood
Ref. Range Notes Blood Sciences Refernce ranges available through the useful information and links page:
https://www.leedsth.nhs.uk/a-z-of-services/pathology/blood-sciences/useful-information-and-links/
Units pmol/L
Telepath PTH2L
ICE Codes LPTH