Parathyroid Hormone (PTH)
PTH is the major hormone involved in calcium homeostasis, and should always be interpreted alongside a concomitant serum calcium result.
| Tube | 04 (EP) - EDTA Plasma |
|---|---|
| ID | Tests&Tubes0089 |
| Additional Information | PTH has a marked diurnal rhythm with a nadir at 10-11am. If hyperparathyroidism is suspected, we suggest that samples are taken in the mid-morning. Raised levels of PTH in the setting of hypercalcaemia are indicative of primary or tertiary hyperparathyroidism. Symptoms of hyperparathyroidism include “bones” (increased turnover), “groans” (abdominal) and “stones” (renal). Note familial hypocalciuric hypercalcaemia (FHH) can cause diagnostic problems, as PTH may also be raised in this disorder. The two conditions can be differentiated by measuring calcium in a 24 hour urine sample. A normal or unmeasurable PTH in a patient with hypocalcaemia is suggestive of hypoparathyroidism. |
| Turn Around | A&E: N/A Day Case: N/A In-Patient: 24 Hours Out-Patient: 24 Hours GP: 72 Hours |
| Send to | Blood Sciences Cross Site |
| Contact | For further details please contact Leeds Pathology customer services: leedsth-tr.pathologycustomerservice@nhs.net. |
| Collection Con | ***** IMPORTANT Serum tube also required for Calcium.***** Minimum volume - 250µl serum / plasma Instructions for Lab Staff: Standard lab processing- No special requirements |
| Sample REQ | Blood |
| Ref. Range Notes | Blood Sciences reference ranges are available through the useful information and links page: https://www.leedsth.nhs.uk/a-z-of-services/pathology/blood-sciences/useful-information-and-links/ |
| Units | pmol/L |
| Telepath | PTH2L |
| ICE Codes | LPTH |
