The Leeds Teaching Hospitals NHS Trust

Prostate Specific Antigen (PSA)

Prostate Specific Antigen (PSA)

A coagulase secreted in semen and synthsised in the prostate. PLEASE NOTE: TEST CAN ONLY BE ADDED TO A SAMPLE WITHIN 8 HOURS OF COLLECTION

Tube 01 (SE) - Serum Gel
ID Tests&Tubes0101
Additional Information PSA is not considered suitable for screening the general population for disease but men over 50 are able to request the test after discussion with their GP.
PSA measurement should be followed up by a DRE. PSA increases with clinical disease stage: PSA >50 ug/L is indicative of metastatic disease with >100 ug/L suggesting bony metastases. PSA is also useful for monitoring treatment of prostatic carcinoma. It is useful to measure PSA post prostatectomy with elevated concentrations being indicative of residual disease. It is also useful for predicting tumour recurrence months before any clinical signs. False negative PSA results are seen in 9% cancer patients.
The minimum repeat interval for PSA is one month.
PSA can be increased following DRE, UTI etc. For more information see: http://www.pathology.leedsth.nhs.uk/pathology/Portals/0/PDFs/BP-2013-05.pdf.
Turn Around A&E: N/A
Day Case: N/A
In-Patient: 24 Hours
Out-Patient: 24 Hours
GP: 24 Hours
Send to Blood Sciences Cross Site
Contact For further details please contact Leeds Pathology customer services: leedsth-tr.pathologycustomerservice@nhs.net.
Collection Con Only measured in males.
Minimum volume - 250µl serum / plasma
Instructions for Lab Staff: Standard lab processing- No special requirements
Sample REQ Blood
Ref. Range Notes Blood Sciences reference ranges are available through the useful information and links page:
https://www.leedsth.nhs.uk/a-z-of-services/pathology/blood-sciences/useful-information-and-links/
Units ug/L
Telepath PSA1L
ICE Codes LPSA