Beta-2 Microglobulin
Beta-2 microglobulin (B2M) is a transmembrane protein found on all cells that carry HLA antigens. Free B2M is a product of cell breakdown. After filtration through the glomeruli B2M is reabsorbed and catabolized by the proximal tubular cells.
| Tube | Immunology |
|---|---|
| ID | 12753 |
| Availability | Weekdays |
| Additional Information | In Multiple Myeloma B2M is a prognostic marker and is used to monitor disease activity. Concentrations are raised in renal tubular dysfunction irrespective of cause. Refer to the International staging system for Multiple Myeloma (serum B2M <3.5mg/L in stage I, >5.5mg/L in stage III). |
| Turn Around | 7 days |
| Send to | Leeds General Infirmary Clinical Immunology Old Medical School Great George Street Leeds LS1 3EX |
| Collection Con | No restrictions |
| Frequency | Daily |
| Sample REQ | Blood |
| Ref. Range (Male) | 1.09 - 2.53 |
| Ref. Range (Female) | 1.09 - 2.53 |
| Ref. Range (Paed) | 1.09 - 2.53 |
| Units | mg/L |
| IP Acute TAT | - Contact Laboratory |
| IP Routine TAT | 7 days |
| GP Acute TAT | - Contact Laboratory |
| GP Routine TAT | 7 days |
| Telepath | B2M1L |
| ICE Codes | IB2M |
