Bethesda Inhibitor Assay
This is a semi-quantitaive assay based on the amount of antibodies to FVIII in the plasma of Haemophilia A patients.
Reported in Bethesda units or as absent
|Tube||05 (CP) - Citrate|
|Additional Information||The assays can be adapted to be sensitive to other clotting factors. One Bethesda unit is defined as the amount of antibody that can neutralise 50% of the FVIII in normal plasma when incubated together for 2 hours at 37C|
|Send to||Specialist Coagulation
Chancellor / Lincoln Wing Link Corridor
St James University Hospital
|Collection Con||All citrate tubes filled to line please - 2 citrate samples required.
Samples must be processed within 6 hours of being taken.
|Ref. Range Notes||Critical telephone values: All new / relapsed positive bethesda assays will be phoned to the appropriate haematology consultant
Normal patients have no inhibitor present
|IP Routine TAT||5 days|