Bethesda Inhibitor Assay
This is a semi-quantitaive assay based on the amount of antibodies to FVIII in the plasma of Haemophilia A patients.
Reported in Bethesda units or as absent
| Tube | 05 (CP) - Citrate |
|---|---|
| ID | 12722 |
| Availability | Weekdays |
| Additional Information | The assays can be adapted to be sensitive to other clotting factors. One Bethesda unit is defined as the amount of antibody that can neutralise 50% of the FVIII in normal plasma when incubated together for 2 hours at 37C |
| Send to | Specialist Coagulation Chancellor / Lincoln Wing Link Corridor Pathology Block 32 St James University Hospital Beckett Street Leeds LS9 7TF |
| Contact | https://www.leedsth.nhs.uk/a-z-of-services/pathology-2/specialist-laboratory-medicine-slm/specialist-coagulation/?stage=Stage |
| Collection Con | All citrate tubes filled to line please - 2 citrate samples required. Samples must be processed within 6 hours of being taken. |
| Sample REQ | Blood |
| Ref. Range Notes | Critical telephone values: All new / relapsed positive bethesda assays will be phoned to the appropriate haematology consultant Normal patients have no inhibitor present |
| Units | Bethesda Units |
| IP Routine TAT | 5 days |
| Telepath | BETH1J |
| ICE Codes | LBETH |
