Dihydrotestosterone
5-alpha-reductase converts testosterone, DHEA and androstenedione into DHT. DHT is responsible for external mascularisation of males. Hence its deficiency leads to ambiguous genitalia in males. Circulating concentrations are of little significance in females.
| Tube | Serum Gel |
|---|---|
| ID | 12632 |
| Availability | Monthly |
| Additional Information | To investigate ambiguous genitalia in neonates and young children. To investigate suspicion of 5alpha- reductase deficiency. Very low levels could indicate an enzyme deficiency. |
| Turn Around | 35 days |
| Send to | Specialist Laboratory Medicine Block 46 St James hospital Beckett Street Leeds LS9 7TF |
| Contact | 1132067043 |
| Advice | 01132064717, stephen.gibbons@nhs.net |
| Collection Con | No restrictions |
| Sample REQ | Blood |
| Ref. Range (Male) | 0.4-1.9 |
| Ref. Range (Female) | <0.5 |
| Ref. Range (Paed) | Paediatric samples - no ranges, interpretive comment added for HCG tests |
| Units | nmol/L |
| IP Routine TAT | 35 days |
| GP Acute TAT | 35 days |
| GP Routine TAT | 35 days |
| Telepath | DHT2J |
| ICE Codes | LDHT |
