Anti-Mullerian hormone (AMH)
**PLEASE NOTE: This test is not routinely available. Requests should be discussed with the Duty Biochemist (0113 39 26922 option 2)** AMH is a protein produced by granulosa cells of the ovaries in females and by Sertoli cells of the testes in males. AMH is considered to be a marker of ovarian reserve with the advantage that blood samples to determine AMH can be taken at any point in a woman's cycle. Success of natural and assisted conception can be predicted. AMH concentrations estimate fertility across normal reproductive life and gradually fall as reproductive potential fails. AMH also can serve as a diagnostic tool for PCOS.
Serum AMH may be used in neonates or children to determine the presence of testicular tissue in disorders of sexual differentiation or development. Prior to puberty, male AMH concentrations are typically much higher than female (around 30 times on average) due to Sertoli cell activity. After the onset of puberty, male AMH concentrations decline so that they overlap with normal female concentrations. AMH in pre-pubertal males is typically greater than 100 pmol/L (and usually significantly higher) and typically much lower than this in pre-pubertal females.
|01 (SE) - Serum Gel
|Indication for requesting AMH: Ovarian function, infertility and gynaecological investigation. Monitoring disease progression or recurrence of granulosa cell tumours.
|Turnaround time stated by Glasgow Royal Infirmary: 14 days
|Blood Sciences LGI
(Test referred to: Glasgow Royal Infirmary)
|For further details please contact Leeds Pathology customer services: email@example.com.
|Full Referred Test details logged internally on the referred test database [BSF2REC17003]http://leedspath.myeqms.com/Administrator/LoadDocADM.asp?ID=82998&Ext=True&CCID=1
|Minimum Volume: 2 mL serum
Instructions to lab: Centrifuge sample, separate and freeze serum.
|Ref. Range Notes
|Interpretation will be provided on report.