The Leeds Teaching Hospitals NHS Trust

Carboxy-terminal collagen crosslinks (CTX)

Carboxy-terminal collagen crosslinks (CTX)

Carboxy-terminal collagen crosslinks (CTX) reflects the resorption of mature collagen by osteoclasts. Used to assess patient response to antiresorptive therapy / compliance. Baseline level required. Levels are increased in any condition with increased osteoclast activity such as immobilisation, Paget's disease, osteoporosis, metastatic cancer, primary hyperparathyroidism.

Tube 04 (EP) - EDTA Plasma
ID Tests&Tubes0165
Additional Information This test is reserved for use by the bone clinic only.
Turn Around Turnaround time stated by Norfolk and Norwich: 2 weeks.
Send to Blood Sciences LGI
(Test referred to: Norfolk and Norwich University Hospital.)
Contact For further details please contact Leeds Pathology customer services: leedsth-tr.pathologycustomerservice@nhs.net.
Collection Con Minimum Volume: 0.5ml EDTA serum.
A single EDTA tube may be sent for both CTX and P1NP. Instructions to lab: Centrifuge sample, separate and freeze plasma.
Sample REQ Blood
Ref. Range Notes Male 0.1 - 0.5 ug/L, Female 0.1 - 0.5 ug/L
Units ug/L
Telepath LGI superset LCTX. SJUH superset JCTX.