Carboxy-terminal collagen crosslinks (CTX)

Carboxy-terminal collagen crosslinks (CTX) reflects the resorption of mature collagen by osteoclasts. Used to assess patient response to antiresorptive therapy / compliance. Baseline level required. Levels are increased in any condition with increased osteoclast activity such as immobilisation, Paget's disease, osteoporosis, metastatic cancer, primary hyperparathyroidism.
Tube | 04 (EP) - EDTA Plasma |
---|---|
ID | Tests&Tubes0165 |
Additional Information | This test is reserved for use by the bone clinic only. |
Turn Around | Turnaround time stated by Norfolk and Norwich: 2 weeks. |
Send to | Blood Sciences LGI (Test referred to: Norfolk and Norwich University Hospital.) |
Contact | For further details please contact Leeds Pathology customer services: leedsth-tr.pathologycustomerservice@nhs.net. |
Collection Con | Minimum Volume: 0.5ml EDTA serum. A single EDTA tube may be sent for both CTX and P1NP. Instructions to lab: Centrifuge sample, separate and freeze plasma. |
Sample REQ | Blood |
Ref. Range Notes | Male 0.1 - 0.5 ug/L, Female 0.1 - 0.5 ug/L |
Units | ug/L |
Telepath | LGI superset LCTX. SJUH superset JCTX. |