Chromogranin A is the major protein within the catecholamine storage vesicles of the adrenal medulla. When catecholamines are released, chromogranin is released. It is also released with polypeptide hormones from other endocrine tissues: pancreatic islet cells, enteroendocrine cells, parathyroid chief cells, thyroid parafollicular C cells and anterior pituitary cells. Chromogranin A may be elevated in patients with various endocrine neoplasms. Clinical indication for measuring: follow-up and management of patients with neuroendocrine tumours and liver metastases. Also a useful marker in lung carcinoids and neuroblastomas.
|Tube||01 (SE) - Serum Gel|
|Additional Information||Should be collected after a 10h fast. Sample should be received in the lab within 3h of collection.|
|Turn Around||Turnaround time stated by Sheffield PRU: 2 weeks.|
|Send to||Blood Sciences LGI
(Test referred to: Sheffield Protein Reference Unit (PRU).)
|Contact||For further details please contact Leeds Pathology customer services: firstname.lastname@example.org.|
|Advice||Full information on all referred tests can be found on the referred tests information database, EQMS reference BSF2REC17003.|
|Collection Con||Instructions to lab: Centrifuge sample, separate and freeze serum within 3h of collection. Lithium heparin or EDTA plasma also acceptable.
Minimum volume: 2 mL serum.
|Ref. Range Notes||< 6 nmol/L|
|Telepath||Supersets LCHRA / JCHRA|
|ICE Codes||LCHRA / JCHRA|