Chromogranin A
Chromogranin A is the major protein within the catecholamine storage vesicles of the adrenal medulla. When catecholamines are released, chromogranin is released. It is also released with polypeptide hormones from other endocrine tissues: pancreatic islet cells, enteroendocrine cells, parathyroid chief cells, thyroid parafollicular C cells and anterior pituitary cells. Chromogranin A may be elevated in patients with various endocrine neoplasms. Clinical indication for measuring: follow-up and management of patients with neuroendocrine tumours and liver metastases. Also a useful marker in lung carcinoids and neuroblastomas.
| Tube | 01 (SE) - Serum Gel |
|---|---|
| ID | Tests&Tubes0169 |
| Additional Information | Should be collected after a 10h fast. Sample should be received in the lab within 3h of collection. |
| Turn Around | Turnaround time stated by Sheffield PRU: 2 weeks. |
| Send to | Blood Sciences LGI (Test referred to: Sheffield Protein Reference Unit (PRU).) |
| Contact | For further details please contact Leeds Pathology customer services: leedsth-tr.pathologycustomerservice@nhs.net. |
| Advice | Full information on all referred tests can be found on the referred tests information database, EQMS reference BSF2REC17003. |
| Collection Con | Instructions to lab: Centrifuge sample, separate and freeze serum within 3h of collection. Lithium heparin or EDTA plasma also acceptable. Minimum volume: 2 mL serum. |
| Sample REQ | Blood |
| Ref. Range Notes | < 6 nmol/L |
| Units | nmol/L |
| Telepath | Supersets LCHRA / JCHRA |
| ICE Codes | LCHRA / JCHRA |
