The Leeds Teaching Hospitals NHS Trust

Copeptin

Copeptin

Information taken from Newcastle website: The Brahms CT-proAVP assay measures the C-terminal precursor fragment of arginine vasopressin (AVP), otherwise known as copeptin. Copeptin is released on an equimolar basis with AVP and therefore measurement of serum/plasma copeptin provides a surrogate measure of AVP concentrations. Clinical indication for requesting: differential diagnosis of polyuria / polydipsia syndromes. Copeptin measurements are of most value when taken under an osmotic stimulus.

Tube 01 (SE) - Serum Gel
ID Tests&Tubes0175
Additional Information **Only available to Endocrinology. Requests should be discussed with the Duty Biochemist, 0113 39 26922, option 2** Please include clinical details and concurrent osmolality with all requests.
Turn Around Turnaround time stated by Newcastle: 4 weeks.
Send to Blood Sciences LGI
(Test referred to: Newcastle Royal Victoria Infirmary.)
Contact For further details please contact Leeds Pathology customer services: leedsth-tr.pathologycustomerservice@nhs.net.
Advice Full information on all referred tests can be found on the referred tests information database, EQMS reference BSF2REC17003.
Collection Con Instructions to lab: Centrifuge sample, separate serum and store in fridge. EDTA plasma or lithium heparin plasma also acceptable.
Minimum volume: 1 mL serum/plasma.
Sample REQ Blood
Ref. Range Notes No single reference range is applicable as copeptin varies according to plasma osmolality in normal individuals. An interpretive comment will be included with each report.
Telepath COPT1R. LGI Superset LCOPT adds SA1R. SJUH Superset JCOPT adds JCHM1L
ICE Codes LCOPT / JCOPT