Valproate
Valproate is used in the treatment of absence seizures. It inhibits the enzymes gamma-aminobutyric acid transaminas (GABA) which results in an increased concentration of GABA in the brain. GABA is an inhibitor of pre and post synaptic discharges in the CNS.
| Tube | 01 (SE) - Serum Gel |
|---|---|
| ID | Tests&Tubes0135 |
| Additional Information | For an adult on a single dose of valproate the half life is 16 hrs but for an adult on chronic therapy the half life is only 12 hrs. |
| Turn Around | A&E: N/A Day Case: 24 Hours In-Patient: 24 Hours Out-Patient: 24 Hours GP: N/A |
| Send to | Blood Sciences LGI |
| Contact | For further details please contact Leeds Pathology customer services: leedsth-tr.pathologycustomerservice@nhs.net. |
| Collection Con | Intensive care units, renal unit, transplant unit, patients on IV heparin use lithium-heparin (Green with Yellow ring) tube. Minimum volume: 500µl serum / plasma Instructions for Lab Staff: Standard lab processing - No special requirements. |
| Sample REQ | Blood |
| Ref. Range Notes | Blood Sciences reference ranges are available through the useful information and links page: https://www.leedsth.nhs.uk/a-z-of-services/pathology/blood-sciences/useful-information-and-links/ |
| Units | mg/L |
| Telepath | VALP2L |
| ICE Codes | LVALP |
