Valproate is used in the treatment of absence seizures. It inhibits the enzymes gamma-aminobutyric acid transaminas (GABA) which results in an increased concentration of GABA in the brain. GABA is an inhibitor of pre and post synaptic discharges in the CNS.
|Tube||01 (SE) - Serum Gel|
|Additional Information||For an adult on a single dose of valproate the half life is 16 hrs but for an adult on chronic therapy the half life is only 12 hrs.|
|Turn Around||A&E: N/A
Day Case: 24 Hours
In-Patient: 24 Hours
Out-Patient: 24 Hours
|Send to||Blood Sciences LGI|
|Contact||For further details please contact Leeds Pathology customer services: firstname.lastname@example.org.|
|Collection Con||Intensive care units, renal unit, transplant unit, patients on IV heparin use lithium-heparin (Green with Yellow ring) tube. Minimum volume: 500µl serum / plasma
Instructions for Lab Staff: Standard lab processing - No special requirements.
|Ref. Range Notes||Blood Sciences reference ranges are available through the useful information and links page: