Amyloid A Protein (SAA)
Serum Amyloid A (SAA) is released from hepatocytes in the acute phase and is the precursor of amyloid A fibrils which are found in amyloidosis (although levels are not predictive of fibril formation). Indicated in patients at risk of Amyloidosis e.g. Rheumatoid arthritis, Inherited Fever Syndromes.
| Tube | Serum Gel |
|---|---|
| ID | 12802 |
| Availability | Weekdays |
| Additional Information | The concentration of SAA in the blood rises greatly in many inflammatory diseases, for example rheumatoid arthritis. Up to 10% of individuals with sustained high SAA values may eventually develop AA amyloidosis. Interpret in conjuction with clinical history, renal function and other acute phase proteins. |
| Turn Around | See https://www.immqas.org.uk/TestItem.asp?id=62 for turn around time, allowing an additional 10 working days for sample processing and reporting. |
| Send to | Samples should be sent to the department of Clinical Immunology at LGI who will refer to appropriate referral lab (Sheffield PRU) |
| Contact | https://www.leedsth.nhs.uk/a-z-of-services/pathology/specialist-laboratory-medicine-slm/immunology-laboratory/ |
| Advice | https://www.leedsth.nhs.uk/a-z-of-services/pathology/specialist-laboratory-medicine-slm/immunology-laboratory/ |
| Collection Con | Turbid, icteric or lipaemic specimens are unsuitable. |
| Frequency | Referred to external laboratory |
| Sample REQ | Blood |
| Ref. Range Notes | See reference range on referral website |
| Units | mg/L |
| IP Acute TAT | See https://www.immqas.org.uk/TestItem.asp?id=62 |
| IP Routine TAT | See https://www.immqas.org.uk/TestItem.asp?id=62 |
| GP Acute TAT | See https://www.immqas.org.uk/TestItem.asp?id=62 |
| GP Routine TAT | See https://www.immqas.org.uk/TestItem.asp?id=62 |
| Telepath | SAA1R |
| ICE Codes | ISAA |
